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PfEMP1 DBLα Sequence Tags in Genomic DNA of P. falciparum Field Isolates from Two Malaria Endemic Sites in Kenya

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dc.contributor.authorMakokha, W Francis
dc.contributor.authorOmar, A Sabah
dc.contributor.authorKimani, T Francis
dc.contributor.authorMagoma, Gabriel
dc.contributor.authorUdu, Rahma
dc.contributor.authorToo, Edwin
dc.contributor.authorShaviya, Nathan
dc.contributor.authorHungu, Charity
dc.date.accessioned2017-01-24T08:03:39Z
dc.date.available2017-01-24T08:03:39Z
dc.date.issued2015
dc.description.abstractMalaria caused by Plasmodium falciparum remains a major cause of childhood morbidity and mortality in sub- Saharan Africa. PfEMP1 protein, coded for by a family of about sixty variant var genes, is a parasite protein found on infected erythrocyte membrane. PfEMP1 protein mediates cytoadherence of infected erythrocytes on endothelial cells which may lead to severe symptoms of malaria. Although PCR amplification of the whole gene is difficult due to high variability, primers targeting the DBLα domain have been designed and used to study pfemp1 genes. This objective of this study was to establish the distribution of DBLα sequence tags in isolates of Plasmodium falciparum from two malaria endemic sites in Kenya.en_US
dc.identifier.issn2224-3186
dc.identifier.issn2225-0921
dc.identifier.urihttp://erepository.mku.ac.ke/handle/123456789/5434
dc.language.isoenen_US
dc.publisherMount Kenya Universityen_US
dc.subjectGenomic DNAen_US
dc.titlePfEMP1 DBLα Sequence Tags in Genomic DNA of P. falciparum Field Isolates from Two Malaria Endemic Sites in Kenyaen_US
dc.typeArticleen_US
dspace.entity.typePublication
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