Publication:
Anti-plasmodial activity of the extracts of some Kenyan medicinal plants

Authors

G.M. Rukunga a, J.W. Gathirwa a, S.A. Omar F.W. Muregi C.N. Muthaura P.G. Kirira G.M. Mungai W.M. Kofi-Tsekpo

Abstract

Ethnopharmacological relevance The spread of drug resistant Plasmodium falciparum strains necessitates search for alternative newer drugs for use against malaria. Medicinal plants used traditionally in preparation of herbal medicines for malaria are potential source of new anti-malarial drugs. Aim of the Study To identify the anti-plasmodial potential of twelve plants used in preparing herbal remedies for malaria in Kilifi and Tharaka districts of Kenya. Materials and Methods Twelve plants used traditionally for anti-malarial therapy in Kilifi and Tharaka districts were extracted with water/methanol yielding twenty-three extracts. The extracts were tested against chloroquine sensitive (NF54) and resistant (ENT30) P. falciparum strains in vitro using 3Hypoxanthine assay.

Cite this Publication
a, G. M. R., a, J. W. G., Omar, S. A., Muregi, F. W., Muthaura, C. N., Kirira, P. G., Mungai, G. M., & Kofi-Tsekpo, W. M. (2009). Anti-plasmodial activity of the extracts of some Kenyan medicinal plants. Journal of Ethnopharmacology. https://erepository.mku.ac.ke/handle/123456789/6143

Keywords

Plasmodium falciparum Kilifi Tharaka

URI

https://doi.org/10.1016/j.jep.2008.10.033
 https://erepository.mku.ac.ke/handle/123456789/6143

Share this Publication

Files

Date

2009-01-21

Journal Title

Journal ISSN

Volume Title

Publisher

Journal of Ethnopharmacology

Collections

Health Sciences