Evaluation of ABOand Rh Blood Groups Among Helicobacter PyloriInfection Among Patients Attending Thika Level 5 Hospital Kiambu, Kenya

Abstract

Background :Blood group A and B carbohydrate are thought to impact the risk of getting H. pylorithrough sticking to the gastric mucosa in the crypts. Knowing the risk factors connected with the infection, interventions and guidance on appropriate preventative measures are required. Methods :The study included 201 patients with dyspepsia symptoms referred from outpatient department for investigation between age 16-75 years. Data on demographic information was gathered before they were given questionnaires. All patientswere investigated for blood group phenotype and rhesus dependent through slide hemagglutination test. H. pyloristool antigen test was also conducted for its positivity. The data was analyzed using SPSS version 25.Results:The frequency of ABO and Rhesusblood group among H. pyloriinfected patients was O, A, B, AB (48.2%), (31.8%), (14.1%), (5.9%) respectively. The majority of the patient were female 51 and 34 males.Conclusion: H. pyloriinfection is an endemic problem that needs to be addressed by improving hygiene, providing purified water and taking additional steps for its eradication. Blood type O are more likely to contract H. pyloriinfections while female and younger adults are more prone to the disease.