Publication: Hepatitis B Virus Immunity Level in Relation to Vaccine Schedule Among Medical Laboratory Health Care Providers in Machakos County, Kenya
Total Views 9
total viewsTotal Downloads 9
total downloadsDate
2022-11-17
Journal Title
Journal ISSN
Volume Title
Publisher
Journal of Medical and Biomedical Laboratory Sciences Research
Cite this Item
Abstract
Background: Hepatitis B Virus (HBV) is categorized in the genus orthohepadnae virus and it encompasses double stranded DNA virus.
Viral infection caused by HBV can either be acute or chronic infection. Acute type of HBV infection occurs in the initial six months
from birth due to exposure to HBV and in adults there might be no symptoms and no complaint of any clinical signs or symptoms.
Methods: Study design used was a cross-sectional study involving all Medical laboratory health care providers was conducted. Hepatitis
B Virus surface antigen rapid test and enzyme linked immunosorbent assay (ELISA) test were used to test the blood samples collected
from the subjects and the results were analyzed using chi-square and verified using Pearson Correlation Coefficient.
Results: The study found that the number of participants who were unvaccinated were 16(17.39%) of which 2 had protective immunity
and 14(66.66%) had low immunity level. Participants who had received first dose of HBV vaccine were 12 of which 3(14.28%) had low
immunity level while 9(12.5%) had protective immunity level. Participants who had received second doses of the vaccine were
11(11.96%) of 2(9.52%) had low HBV immunity level where as 9(12.5%) had protective immunity level. Participants who had complete
HBV vaccine doses (3 doses) were 52(56.52%) of which 2(9.52%) had low immunity level while 50(70.42%) had protective immunity
level.
Conclusion: The research concluded there is need for completion of HBV vaccine schedule of the three doses so as to increase the
immunity level since 70.42% of respondents who had completed the three doses had protective immunity levels above the cutoff point
recommended by the WHO (≥10 mIU/ml).It is advisable to get a booster vaccine after completion of the three HBV doses according to
the vaccine schedule
Description
Keywords
Hepatitis B Virus, Immunity, Vaccination, Healthcare providers