Publication:

Antibacterial and antioxidant activities of methanol rhizome extract of zingiber officinale

Antimicrobial drug resistance is one of the challenging problems that the world is facing Currently. This situation is worsening each day due to the high cost of searching new Antimicrobial agents. Additionally, the slow rate of new drug discovery is greatly contributing To the worsening of this state. The oxidation process in the body that results into free radicals Has as well resulted into oxidative stress which is an etiology in many chronic conditions such As cancer. These chronic conditions are not easy to prevent with the conventional drugs hence Need for alternatives. However, nature has shown to be the savior of this devastating global Challenge by offering alternative agents with antimicrobial and antioxidant properties. These Agents include the products from plants, herbs and shrubs with medicinal values, minerals and Other products. This study aimed at evaluating the antibacterial and antioxidant activities of Methanol rhizome extract of zingiber officinale. Disc diffusion technique and dpph free Radical scavenging assay were used as methods for evaluating antibacterial and antioxidant. Ciprofloxacin and l-ascorbic acid were used as the standard antibiotic and antioxidant Respectively. The antibacterial activity was tested aginst pure cultures of staphylococcus Aureus, pseudomonas aeruginosa and e.coli. The results showed that the extract of zingiber Officinale was more active against psudomoan aeruginosa followed by staphylococcus aureus. The extract of zingiber officinale was less active against e.coli. The antioxidant activity results Showed that l-ascorbic acid recorded significantly higher percentage radical scavenging Activity as compared to the extract of zingiber officinale at all concentration levels (p<0.05). In conclusion it’s evident that zingiber officinale has antibacterial and antioxidant properties.