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Anti-plasmodial activity of the extracts of some Kenyan medicinal plants.

Rukunga, GM; Gathirwa, JW; Omar, SA; Muregi, FW; Muthaura, CN; Kirira, PG; Mungai, GM; Kofi-Tsekpo, WM (J Ethnopharmacol, 2009-01)

ETHNOPHARMACOLOGICAL RELEVANCE: The spread of drug resistant Plasmodium falciparum strains necessitates search for alternative newer drugs for use against malaria. Medicinal plants used traditionally in preparation of ...

The in vitro anti-plasmodial and in vivo anti-malarial efficacy of combinations of some medicinal plants used traditionally for treatment of malaria by the Meru community in Kenya

Gathirwa, JW; Rukunga, GM; Njagi, EN; Omar, SA; Mwitari, PG; Guantai, AN; Tolo, FM; Kimani, CW; Muthaura, CN; Kirira, PG; Ndunda, TN; Amalemba, G; Mungai, GM; Ndiege, IO (J Ethnopharmacol, 2008-01-17)

The use of herbal drugs as combinations has existed for centuries in several cultural systems. However, the safety and efficacy of such combinations have not been validated. In this study, the toxicity, anti-plasmodial and ...

Anti-plasmodial activity of the extracts and two sesquiterpenes from Cyperus articulatus

Rukunga, GM; Muregi, F. M.; Omar, SA; Gathirwa, JW; Muthaura, CN; Peter, MG; Heydenreich, M; Mungai, GM (Kenya Medical Research Institute (KEMRI), 2008-04)

Two sesquiterpenes, corymbolone and mustakone, isolated from the chloroform extract of the rhizomes of Cyperus articulatus, exhibited significant anti-plasmodial properties. Mustakone was approximately ten times more active ...

The antiplasmodial activity of spermine alkaloids isolated from Albizia gummifera.

Rukunga, GM; Muregi, Francis W.; Tolo, F. M.; Omar, SA; Mwitari, P; Muthaura, CN; Omlin, F.; Lwande, W,; Hassanali, A.; Githure, J; Iraqi, FW; Mungai, GM; Kraus, W,; Kofi-Tsekpo, WM (Kenya Medical Research Institute (KEMRI), 2007-12)

In the present study the methanolic extract of Albizia gummifera was fractionated into various fractions. These fractions were tested against choroquine sensitive (NF54) and resistant (ENT30) strains of Plasmodium falciparum. ...

Anti-plasmodial activity of the extracts and two sesquiterpenes from Cyperus articulatus.

Rukunga, GM; Muregi, FW; Osmar, SA; Gathirwa, JW; Muthaura, CN; Peter, MG; Heydenreich, M; Mungai, GM (Mount Kenya University, 2008-04)

Two sesquiterpenes, corymbolone and mustakone, isolated from the chloroform extract of the rhizomes of Cyperus articulatus, exhibited significant anti-plasmodial properties. Mustakone was approximately ten times more active ...

The antiplasmodial activity of spermine alkaloids isolated from Albizia gummifera.

Rukunga, GM; Muregi, FW; Tolo, FM; Omar, SA; Mwitari, P; Muthaura, CN; Omlin, F; Lwande, W; Hassanah, A; Githure, J; Iraqi, FW; Mungai, GM; Kraus, W; Kofi-Tsekpo, WM (Mount Kenya University, 2007-12)

In the present study the methanolic extract of Albizia gummifera was fractionated into various fractions. These fractions were tested against choroquine sensitive (NF54) and resistant (ENT30) strains of Plasmodium falciparum. ...