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    Resistance of a rodent malaria parasite to a thymidylate synthase inhibitor induces an apoptotic parasite death and imposes a huge cost of fitness. 

    Muregi, Francis W.; Ohta, Isao; Masato, Uchijima; Kino, Hideto; Ishih, Akira (PubMedCentral, 2011-06-16)
    BACKGROUND: The greatest impediment to effective malaria control is drug resistance in Plasmodium falciparum, and thus understanding how resistance impacts on the parasite's fitness and pathogenicity may aid in malaria ...
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    Resistance of a Rodent Malaria Parasite to a Thymidylate Synthase Inhibitor Induces an Apoptotic Parasite Death and Imposes a Huge Cost of Fitness 

    Muregi, W Francis; Ohta, Isao; Maseto, Uchijina; Kino, Hideto; Ishih, Akira (Mount Kenya University, 2011-06)
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    Next-Generation Antimalarial Drugs: Hybrid Molecules as a New Strategy in Drug Design 

    Muregi, Francis W.; Ishih, Akira (Department of Infectious Diseases, Hamamatsu University School of Medicine, Hamamatsu, Japan. 2 Centre for Biotechnology Research and Development, Kenya Medical Research Institute (KEMRI) Nairobi, Kenya),, 2010)
    Malaria is a disease that affects nearly 40% of the global population, and chemotherapy remains the mainstay of its control strategy. The global malaria situation is increasingly being exacerbated by the emergence of ...

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    Ishih, Akira (3)
    Kino, Hideto (2)Muregi, Francis W. (2)Ohta, Isao (2)Masato, Uchijima (1)Maseto, Uchijina (1)Muregi, W Francis (1)SubjectAminoquinolines (1)Antimalarial resistance (1)Malaria (1)Malarial Chemotherapy (1)Malarial conjugates (1)Trioxaquines and trioxolaquines (1)... View MoreDate Issued2011 (2)2010 (1)Has File(s)Yes (3)

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