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    Levels of Adherence to Coartem© in the Routine Treatment of Uncomplicated Malaria in Children Aged Below Five Years, in Kenya. 

    Ogolla, Jared Otieno; Ayaya, Samuel Omulando; Otieno, Christina Agatha (Iranian Journal of Public Health, 2013)
    This study sought to determine the level of adherence to Coartem© in the routine treatment of uncomplicated malaria among children under the age of five years in Nyando district, Kenya. Seventy-three children below the ...
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    Novel Rational Drug Design Strategies with Potential to Revolutionize Malaria Chemotherapy 

    Muregi, F W; Kirira, P G; Ishih, A (Mount Kenya University, 2011)
    Efforts to develop an effective malaria vaccine are yet to be successful and thus chemotherapy remains the mainstay of malaria control strategy. Plasmodium falciparum, the parasite that causes about 90% of all global ...
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    Resistance of a Rodent Malaria Parasite to a Thymidylate Synthase Inhibitor Induces an Apoptotic Parasite Death and Imposes a Huge Cost of Fitness 

    Muregi, W Francis; Ohta, Isao; Maseto, Uchijina; Kino, Hideto; Ishih, Akira (Mount Kenya University, 2011-06)
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    Shrinking a large dataset to identify variables associated with increased risk of Plasmodium falciparum infection in Western Kenya 

    TREMBLAY, M.; DAHM1, J. S.; WAMAE, C. N.; GLANVILLE, W. A. DE; FÈVRE, E. M.; DÖPFER, D. (Cambridge University Press, 2015-04-16)
    Large datasets are often not amenable to analysis using traditional single-step approaches. Here, our general objective was to apply imputation techniques, principal component analysis (PCA), elastic net and generalized ...
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    Prevalence of Taenia solium cysticercosis in pigs entering the food chain in western Kenya 

    Toye, Philip; Glanville, William Anson de; Cook, Elizabeth Anne Jess; Wamae, Claire Njeri Wamae; Fèvre, Eric Maurice (open access at Springerlink.com, 2015-11-18)
    Three hundred forty-three pigs slaughtered and marketed in western Kenya were subjected to lingual examination and HP10 Ag-ELISA for the serological detection of Taenia solium antigen. When estimates were adjusted for ...
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    PfEMP1 DBLα Sequence Tags in Genomic DNA of P. falciparum Field Isolates from Two Malaria Endemic Sites in Kenya 

    Makokha, W Francis; Omar, A Sabah; Kimani, T Francis; Magoma, Gabriel; Udu, Rahma; Too, Edwin; Shaviya, Nathan; Hungu, Charity (Mount Kenya University, 2015)
    Malaria caused by Plasmodium falciparum remains a major cause of childhood morbidity and mortality in sub- Saharan Africa. PfEMP1 protein, coded for by a family of about sixty variant var genes, is a parasite protein found ...
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    Fitness cost of resistance for lumefantrine and piperaquine-resistant Plasmodium berghei in a mouse model 

    Gimode, R Winnie; Miboi, M Daniel; Kimani, T Francis; Wamakima, N Hannah; Burugu, W Marion; Francis, W Muregi (Mount Kenya University, 2015)
    The evolution of drug-resistant parasites is a major hindrance to malaria control, and thus understanding the behaviour of drug-resistant mutants is of clinical relevance. The study aimed to investigate how resistance ...
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    The Influence of Socio-economic, Behavioural and Environmental Factors on Taenia spp. Transmission in Western Kenya: Evidence from a Cross-Sectional Survey in Humans and Pigs 

    Wardrop, Nicola A.; Thomas, Lian F.; Atkinson, Peter M.; Glanville, William A. de; Cook, A. J. Cook; Wamae, C. Njeri; Gabriël, Sarah; Dorny, Pierre; Harrison, Leslie J. S.; Fèvre, Eric M. (Wardrop et al, 2015-12-07)
    Taenia spp. infections, particularly cysticercosis, cause considerable health impacts in endemic countries. Despite previous evidence of spatial clustering in cysticercosis and the role of environmental factors (e.g. ...
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    Understanding the relationship between prevalence of microfilariae and antigenaemia using a model of lymphatic filariasis infection 

    Irvinea, Michael A.; Njengab, Sammy M.; Gunawardenac, Shamini; Wamaee, Claire Njeri; Cano, Jorge; Brooker, Simon J.; Hollingswortha, T. Deirdre (Oxford University Press, 2016)
    Background: Lymphatic filariasis is a debilitating neglected tropical disease that affects impoverished communities. Rapid diagnostic tests of antigenaemia are a practical alternative to parasitological tests of ...
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    Novel drug targets in malaria parasite with potential to yield antimalarial drugs with long useful therapeutic lives. 

    Muregi, FW; Wamakima, HN; Kimani, FT (Mount Kenya University, 2012)
    The status of chemotherapy as the main strategy in malaria control is rapidly being eroded by development of drug resistant Plasmodia, causing malaria to be dubbed a "re-emerging disease". To counter this misfortune, there ...
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    AuthorIshih, Akira (3)Muregi, Francis W. (3)Kimani, T Francis (2)Kino, Hideto (2)Kirira, P. G. (2)Muregi, FW (2)Ohta, Isao (2)Wamakima, HN (2)Akparibo, Robert (1)Atkinson, Peter M. (1)... View MoreSubjectMalaria (4)Antimalarial drugs (3)Plasmodium falciparum (3)Antimalarial resistance (2)Malarial Chemotherapy (2)Aminoquinolines (1)Antigenaemia, Elimination programme, Lymphatic filariasis, Microfilaraemia, Prevalence surveys (1)Antimalaria (1)Antimalarial design (1)Antimalarial Drugs (1)... View MoreDate Issued2011 (6)2015 (6)2012 (3)2013 (3)2010 (2)2014 (2)2016 (1)Has File(s)Yes (23)

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