Publication:

Antimicrobial activities of uvariodendron anisatum fractions

Conventional antimicrobial agents available for treating infections caused by microorganisms pose a wide range of challenges which include antimicrobial resistance & severe side effects. In an attempt to develop potent drugs for the treatment of infectious diseases, antimicrobial agents in natural products have been widely researched. This research project aimed at establishing the antimicrobial effects of Uvariodendron anisatum Fractions .The Fractions were obtained through column chromatography from Uvariodendron anisatum root extract which was prepared by maceration. Antibacterial activity against Escherichia coli & Staphylococcus aureus was investigated via disk diffusion method. Results obtained did indicate that the Fractions possess antibacterial activity. It can therefore be concluded that the root extracts of Uvariodendron anisatum have Fractions of great ethno medical importance & can be used for treatment of infections caused by Escherichia coli & Staphylococcus aureus.It is thus recommended that bioassay guided techniques be utilized in search of the active extracts from this plant. Furthermore, there is need to establish profiles of in vivo antibacterial effects of the isolated Fractions.