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PfEMP1 DBLα Sequence Tags in Genomic DNA of P. falciparum Field Isolates from Two Malaria Endemic Sites in Kenya (Journal of Natural Sciences Research, 2015)Background Malaria caused by Plasmodium falciparum remains a major cause of childhood morbidity and mortality in sub- Saharan Africa. PfEMP1 protein, coded for by a family of about sixty variant var genes, is a parasite ...
Fitness cost of resistance for lumefantrine and piperaquine-resistant Plasmodium berghei in a mouse model (Gimode et al. Malaria Journal, 2015)Background: The evolution of drug-resistant parasites is a major hindrance to malaria control, and thus understanding the behaviour of drug-resistant mutants is of clinical relevance. The study aimed to investigate how ...
(Journal of Natural Sciences Research, 2015)Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) found on the surface of infected erythrocytes (IEs) mediate antigenic variation during P. falciparum infection enabling the parasite evade host immune responses ...